Anti-Hu CD147 Purified Low Endotoxin

EXBIO

Mouse Monoclonal to CD147 / Basigin / Neurothelin

7

The antibody MEM-M6/6 recognizes extracellular Ig domain D2 (membrane proximal) of CD147 (Neurothelin), a 50-60 kDa type I transmembrane glycoprotein primarily expressed on all leukocytes, red blood cells, platelets and endothelial cells; it is not expres

Functional application: The antibody MEM-M6/6 (high-affinity mAb of unique epitope specificity) inhibits anti-CD3-induced T cell activation. Flow cytometry: recommended dilution: 1-4 microg/ml. Western blotting: Positive control: 293 human fibroblastoid cell line, non-reducing conditions.

Functional Assay, Flow Cytometry, Western Blot

Research Use Only

MEM-M6/6

1 mg/ml

IgG1

CD147 (basigin, neurothelin, OX-47, 5A11, CE9, M6) also known as EMMPRIN (extracellular matrix metalloproteinase inducer) or TCSF (tumour cell-derived collagenase-stimulatory factor) is an ubiquitously expressed cell surface protein with multiple glycosylated forms. The highest level of CD147 expression is on metabolically active cells, such as lymphoblasts, inflammatory cells, brown adipocytes and malignant tumour cells. CD147 has multiple functions, including facilitating of cell surface expression of monocarboxylate transporter proteins and extracellular matrix metalloproteinases, regulation of integrin functions, it plays roles in cell development and activation, fetal development or retinal function.

Human

2°C to 8°C

12352203