Anti-Hu CD70 Purified

EXBIO

Mouse Monoclonal to CD70

7

The mouse monoclonal antibody Ki-24 recognizes an extracellular epitope of CD70, an approximately 50 kDa type II transmembrane glycoprotein expressed on activated lymphocytes and some B cell leukemias.

Flow cytometry: Recommended dilution: 1-5 microg/ml.

Flow Cytometry

Research Use Only

Ki-24

1 mg/ml

IgG3

CD70, also known as TNFSF7 or CD27L, is a 50 kDa type II transmembrane glycoprotein of the TNF superfamily. It is expressed mainly on activated lymphocytes, including NK cells, and forms trimeric structure. CD70 plays a role in T-cell activation, proliferation and differentiation, in enhancing the generation of cytolytic T cells, and in long-term maintenance of T cell memory. It is also involved in B cell differentiation induced by activated plasmacytoid dendritic cells, which also express CD70.

Human

2°C to 8°C

12352203