Anti-Hu CD9 Purified Azide Free

EXBIO

Mouse Monoclonal to CD9

7

The antibody MEM-61 recognizes an epitope on second extracellular domain (EC2) of CD9 antigen, a 24 kDa transmembrane protein expressed on platelets, monocytes, pre-B lymphocytes, granulocytes and activated T lymphocytes.

Functional application: The antibody MEM-61 induces FcgammaR-dependent platelet aggregation. Flow cytometry: Recommended dilution: 1-4 microg/ml. Western blotting: Recommended dilution: 2-4 microg/ml, non-reducing conditions. Immunohistochemistry (paraffin sections): Recommended dilution: 10 microg/ml, positive tissue: prostate.

Functional Assay, Flow Cytometry, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin, Other Application

Research Use Only

MEM-61

1 mg/ml

IgG1

CD9 belongs to proteins of tetraspanin family that orchestrate cholesterol-associated tetraspanin-enriched signaling microdomains within the plasma membrane, forming complexes with each other as well as with integrins, membrane-anchored growth factors and other proteins. CD9 is involved in cell motility, osteoclastogenesis, neurite outgrowth, myotube formation, and sperm-egg fusion, plays roles in cell attachment and proliferation and is necessary for association of heterologous MHC II molecules on the dendritic cell plasma membrane which is important for effective T cell stimulation. CD9 is also considered as metastasis suppressor in solid tumors.

Human

2°C to 8°C

12352203