Anti-DLL4 Purified Low Endotoxin

EXBIO

Mouse Monoclonal to DLL4

7

The mouse monoclonal antibody MHD4-46 recognizes the extracellular domain of DLL4 (Delta-like ligand 4), a type I transmembrane protein which plays an important role in vascular development.

Functional application: Blocking. Flow cytometry: Recommended dilution: 1-4 microg/ml

Functional Assay, Flow Cytometry

Research Use Only

MHD4-46

1 mg/ml

IgG1

DLL4 (Delta-like 4) is one of five ligands of Notch receptors. It is up-regulated at sites of physiological and pathological angiogenesis, whereas its expression is low in most adult normal tissues. It is also highly expressed in human clear-cell renal carcinomas, bladder cancers, and breast cancers. Blocking the DLL4-Notch interaction seems to be a promissing therapeutic approach.

Human

2°C to 8°C

12352203