Anti-Hu IgD Purified

EXBIO

Mouse Monoclonal to IgD

7

The mouse monoclonal antibody IA6-2 recognizes human immunoglobulin D.

Flow cytometry: Recommended dilution: 2-4 microg/ml.

Flow Cytometry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen

Research Use Only

IA6-2

1 mg/ml

IgG2a

Immunoglobulin D (IgD) is expressed on the surface of naive mature B cells, thus later than IgM, and is coexpressed with it then. Triggered by antigen binding, it signals through the CD79 complex to activate the B cells. Expression of IgD is lost after the isotype switch. Soluble IgD is present in very small amounts in the serum. IgD can bind to basophils and mast cells to activate them in an IgE-independent way to participate in respiratory immune defense.

Human

2°C to 8°C

12352203