Mouse recombinant LIGHT protein, AF

Boster Bio

Mouse recombinant LIGHT protein, AF

9

Other Application

Research Use Only

>98%

Tumor necrosis factor ligand superfamily member 14

LIGHT, also known as TNFSF14 is a member of the TNF superfamily that produced by multiple immune cells such as activated T cells and immature dendritic cells (DCs). Mouse LIGHT shares 79% sequence homology with human LIGHT. LIGHT is a 29 kDa type II transmembrane protein, which serves as a ligand for both lymphotoxin beta receptor (LTbetaR) and TNFSF signaling receptors (TNFRSF14/HVEM). Besides, LIGHT can amplify NF-kB signaling pathway in T cells when presencing anti-CD3 antibody treatment. Additionally, LIGHT is able to stimulate T cell proliferation and IFN expression via interacting with TNFRS13 /HVEM.

E.coli

-20°C,-20°C or -80°C,2°C to 8°C

12352202