mPGES1-IN-3
HY-100864
CAS Number1469976-70-2
Product group Chemicals
Molecular Weight538.85
Overview
- SupplierMedChem Express
- Product NamemPGES1-IN-3 [1469976-70-2]
- Delivery Days Customer10
- CAS Number1469976-70-2
- Molecular FormulaC24H16ClF5N4O3
- Molecular Weight538.85
- Scientific DescriptionmPGES1-IN-3 (Compound 17d) is a potent and selective microsomal prostaglandin E2 synthase-1 ( mPGES-1 ) inhibitor, which exhibits excellent mPGES-1 enzyme ( IC 50 : 8 nM), cell (A549 IC 50 : 16.24 nM) and human whole blood potency (IC 50 : 249.9 nM) [1] .
- SMILESO=C(NC1=CC(F)=CC(C(F)(F)F)=C1)C2=C(OCCO3)C3=C(N(C)C(NC4=C(Cl)C=CC=C4F)=N5)C5=C2
- UNSPSC12352200