Bio-Connect

mPGES1-IN-3

HY-100864
MedChem Express
CAS Number1469976-70-2
Product group Chemicals
Molecular Weight538.85
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Overview

  • Supplier
    MedChem Express
  • Product Name
    mPGES1-IN-3 [1469976-70-2]
  • Delivery Days Customer
    10
  • CAS Number
    1469976-70-2
  • Molecular Formula
    C24H16ClF5N4O3
  • Molecular Weight
    538.85
  • Scientific Description
    mPGES1-IN-3 (Compound 17d) is a potent and selective microsomal prostaglandin E2 synthase-1 ( mPGES-1 ) inhibitor, which exhibits excellent mPGES-1 enzyme ( IC 50 : 8 nM), cell (A549 IC 50 : 16.24 nM) and human whole blood potency (IC 50 : 249.9 nM) [1] .
  • SMILES
    O=C(NC1=CC(F)=CC(C(F)(F)F)=C1)C2=C(OCCO3)C3=C(N(C)C(NC4=C(Cl)C=CC=C4F)=N5)C5=C2
  • UNSPSC
    12352200