MPro N3

TargetMol Chemicals

MPro N3

107

884650-98-0

Chemical

MPro N3

C35H48N6O8

680.79

Coronavirus main protease (Mpro) inhibitor (respective IC50 values are 2.7, 4 and 8.8 uM for MHV-A29, HCoV-229E and FOPV replication in vitro). Inhibits viral cell infection in an MHV plaque reduction assay. Also inhibits SARS-CoV-2 viral cell entry in a plaque reduction assay (IC50 = 16.8 uM).

3 years

[C@@H](C[C@H]1C(=O)NCC1)(NC([C@@H](NC([C@@H](NC([C@@H](NC(=O)C=2C=C(C)ON2)C)=O)C(C)C)=O)CC(C)C)=O)/C=C/C(OCC3=CC=CC=C3)=O

-20°

12352200