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MR-16728 (hydrochloride)

HY-100981
MedChem Express
CAS Number207403-36-9
Product group Chemicals
Molecular Weight393.01
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Overview

  • Supplier
    MedChem Express
  • Product Name
    MR-16728 (hydrochloride)
  • Delivery Days Customer
    9
  • CAS Number
    207403-36-9
  • Molecular Formula
    C23H37ClN2O
  • Molecular Weight
    393.01
  • Scientific Description
    MR-16728 hydrochloride is a compound that promotes the release of acetylcholine and has activity that enhances the release of acetylcholine. MR-16728 hydrochloride inhibits acetylcholine release induced by KCl depolarization. MR-16728 hydrochloride also inhibits Ca(2+)-ATPase activity in pure presynaptic membranes. The half-maximal effect of MR-16728 hydrochloride occurs at a concentration of 13.5 microM. MR-16728 hydrochloride significantly enhances the release of acetylcholine in the presence of low concentrations of calcium (approximately 10 microM range). Enhanced acetylcholine release was also observed with MR-16728 hydrochloride in proteoliposomes loaded with mediator proteins [1] .
  • SMILES
    O=C(NCCCN1CCCCCC1)C(C2CCCCC2)C3=CC=CC=C3.Cl
  • UNSPSC
    12352200