Bio-Connect

MS4078 [2229036-62-6]

Research Use Only
ORB611306
Biorbyt
CAS Number2229036-62-6
Product group Chemicals
Molecular Weight914.47
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    Biorbyt
  • Product Name
    MS4078 [2229036-62-6]
  • Delivery Days Customer
    16
  • CAS Number
    2229036-62-6
  • Certification
    Research Use Only
  • Molecular Formula
    C45H52ClN9O8S
  • Molecular Weight
    914.47
  • Scientific Description
    MS4078 is a novel PROTAC (degrader) of ALK, potently decreases cellular levels of oncogenic active ALK fusion proteins in a concentration- and time-dependent manner in SU-DHL-1 lymphoma and NCI-H2228 lung cancer cells (DC50=11 nM).
  • SMILES
    CC(C)S(C1=C(NC2=NC(NC3=C(OC(C)C)C=C(C4CCN(CC(NCCNC5=C(C(N(C6C(NC(CC6)=O)=O)C7=O)=O)C7=CC=C5)=O)CC4)C(C)=C3)=NC=C2Cl)C=CC=C1)(=O)=O
  • UNSPSC
    12352200