MS4078 [2229036-62-6]

ORB611306
CAS Number2229036-62-6
Product group Chemicals
Molecular Weight914.47
Overview
- SupplierBiorbyt
- Product NameMS4078 [2229036-62-6]
- Delivery Days Customer16
- CAS Number2229036-62-6
- CertificationResearch Use Only
- Molecular FormulaC45H52ClN9O8S
- Molecular Weight914.47
- Scientific DescriptionMS4078 is a novel PROTAC (degrader) of ALK, potently decreases cellular levels of oncogenic active ALK fusion proteins in a concentration- and time-dependent manner in SU-DHL-1 lymphoma and NCI-H2228 lung cancer cells (DC50=11 nM).
- SMILESCC(C)S(C1=C(NC2=NC(NC3=C(OC(C)C)C=C(C4CCN(CC(NCCNC5=C(C(N(C6C(NC(CC6)=O)=O)C7=O)=O)C7=CC=C5)=O)CC4)C(C)=C3)=NC=C2Cl)C=CC=C1)(=O)=O
- UNSPSC12352200