MS417

MedChem Express

MS417 [916489-36-6]

10

916489-36-6

Research Use Only

99.79

C20H19ClN4O2S

414.91

MS417 is a selective BET-specific BRD4 inhibitor, binds to BRD4-BD1 and BRD4-BD2 with IC 50 s of 30, 46 nM and K d s of 36.1, 25.4 nM, respectively, with weak selectivity at CBP BRD ( IC 50 , 32.7 microM).

O=C(OC)C[C@H]1C2=NN=C(C)N2C3=C(C(C)=C(C)S3)C(C4=CC=C(Cl)C=C4)=N1

2°C to 8°C

12352200