MS48107

MedChem Express

MS48107 [2375070-79-2]

10

2375070-79-2

Research Use Only

99.90

C23H20FN5O2

417.44

MS48107 is a potent and selective positive allosteric modulator of G protein-coupled receptor 68 (GPR68). MS48107 is selective for GPR68 over the closely related proton GPCRs, neurotransmitter transporters, and hERG ion channels. MS48107 can readily cross the blood-brain barrier (BBB) in mice[1].

OCC1=CC=CC(F)=C1C2=NC(N)=NC(NCC3=CC=C(OC4=CC=CC=C4)C=C3)=N2

-20°C,2°C to 8°C

12352200