MS7 [1593654-46-6]

TargetMol Chemicals

MS7 [1593654-46-6]

9

Research Use Only

C24H27N5O2S2

481.63

MS7 is a potent inhibitor of nicotinamide phosphoribosyltransferase (NAMPT), a rate-limiting enzyme in the NAD+ biosynthesis pathway that converts nicotinamide to nicotinamide mononucleotide, which is subsequently transformed into NAD+. NAMPT is overexpressed in various cancer cells to sustain the NAD+ supply required for rapid proliferation. The derivative of MS7, PROTAC A7, serves as an effective NAMPT degrader. MS7 is utilized in cancer research.

O=S(=O)(C1=CC=C(C=C1)NC(=S)NCC=2C=NC=CC2)N3CCN(CC=4C=CC=CC4)CC3

-20°C

12352200