mStab1-1.26, InVivoPure+
AK726P+
ApplicationsOther Application
Product group Antibodies
ReactivityMouse, Rat
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Overview
- SupplierInVivo Biotech
- Product NamemStab1-1.26, InVivoPure+
- Delivery Days Customer5
- ApplicationsOther Application
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID1.26
- Concentration1.00 mg/ml
- ConjugateUnconjugated
- Estimated Purity>=90%
- FormulationLiquid
- HostMouse
- IsotypeIgG1
- Protein IDQ8R4Y4
- Protein NameStabilin-1
- Scientific DescriptionmStab1-1.26, InVivoPure+ is a mouse monoclonal antibody against mouse Stabilin-1 (UniProt entry: Q8R4Y4), also known as Clever-1 or FEEL-1. Stabilin-1 is a scavenger receptor expressed by sinusoidal endothelial cells (ECs) in the liver, lymph nodes, spleen, and bone marrow [1]. Stabilin-1 is expressed in human breast cancer and supports tumor growth [2]. It is found on subset of macrophages that mediate tissue homeostasis and is involved in liver fibrosis [3]. mStab1-1.26 or mStabilin-1 (clone 1.26) is first mentioned by Schledzewski et al. (2006) [4]. To generate the antibody, a recombinant mouse stabilin-1 fragment (residues 1-710 of Q8R4Y4) fused to mouse IgG2b-Fc was purified from stably-transfected HEK293 cells and used to immunize stabilin-1 knockout mice. mStab1-1.26 recognizes stabilin-1 in rat and mouse. The antibody is produced exclusively under serum-free conditions from hybridoma and purified through one-step purification with Protein-G affinity chromatography.
- ReactivityMouse, Rat
- UNSPSC12352203