Mtb-IN-2

MedChem Express

Mtb-IN-2

14

Research Use Only

C17H12N2O4

308.29

Mtb-IN-2 (compound 10c) is an antimicrobial agent against Mycobacterium tuberculosis (Mtb), without cytotoxicity. Mtb-IN-2 significantly decreases colony-forming units (CFU) in spleen of murine tuberculosis models, and distinguishes both drug-sensitive and drug-resistant Mtb H37Rv strains. Mtb-IN-2 affects methionine metabolism but not folate pathway directly.

O=C(NC1=CC(O)=C(C(O)=O)C=C1)C2=NC3=C(C=C2)C=CC=C3

12352200