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Mu-Conotoxin SIIIA

Research Use Only
PCN-4440-v
Biosynth
Product group Proteins / Signaling Molecules
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Overview

  • Supplier
    Biosynth
  • Product Name
    Mu-Conotoxin SIIIA
  • Delivery Days Customer
    5
  • Certification
    Research Use Only
  • Scientific Description
    micro-Conotoxin SIIIA (Marine Snail, Conus striatus) Pyr-Asn-Cys-Cys-Asn-Gly-Gly-Cys-Ser-Ser- Lys-Trp-Cys-Arg-Asp-His-Ala-Arg-Cys-Cys-NH2 (Disulfide bonds between Cys3-Cys13, Cys4-Cys19, and Cys8-Cys20) (M.W. 2207.5) C83H123N33O27S6 Tetrodotoxin-Resistant Na+ Channel Blocker with Analgesic Activity 1) G. Bulaj, P.J. West, J.E. Garrett, M. Marsh, M.-M. Zhang, R.S. Norton, B.J. Smith, D. Yoshikami, and B.M. Olivera, Biochemistry, 44, 7259 (2005). (Original; Primary Structure & Pharmacol.) 2) S. Yao, M.-M. Zhang, D. Yoshikami, L. Azam, B.M. Olivera, G. Bulaj, and R.S. Norton, Biochemistry, 47, 10940 (2008). (Solution Structure & Pharmacol.) 3) C.-Z. Wang, H. Zhang, H. Jiang,W. Lu, Z.-Q. Zhao, and C.-W. Chi, Toxicon, 47, 122 (2006). (Pharmacol.) 4) B.R. Green, P. Catlin, M.-M. Zhang, B. Fiedler, W. Bayudan, A. Morrison, R.S. Norton, B.J. Smith, D. Yoshikami, B.M. Olivera, and G. Bulaj, Chem. Biol., 14, 399 (2007). (Pharmacol.)
  • Source
    (Marine Snail, Conus striatus)
  • UNSPSC
    12352202