![MUC1 / CA15-3 / EMA / CD227 (Epithelial Marker)(115D8), CF640R conjugate, 0.1mg/mL [26628-22-8] MUC1 / CA15-3 / EMA / CD227 (Epithelial Marker)(115D8), CF640R conjugate, 0.1mg/mL [26628-22-8]](https://biotium.com/wp-content/uploads/2021/02/view_image-7.jpeg)
MUC1 / CA15-3 / EMA / CD227 (Epithelial Marker)(115D8), CF640R conjugate, 0.1mg/mL [26628-22-8]
BNC400612
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityBovine, Human, Mouse
TargetMUC1
Overview
- SupplierBiotium
- Product NameMUC1 / CA15-3 / EMA / CD227 (Epithelial Marker)(115D8), CF640R conjugate, 0.1mg/mL
- Delivery Days Customer9
- ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID115D8
- Concentration0.1 mg/ml
- ConjugateOther Conjugate
- Gene ID4582
- Target nameMUC1
- Target descriptionmucin 1, cell surface associated
- Target synonymsADMCKD; ADMCKD1; ADTKD2; breast carcinoma-associated antigen DF3; CA 15-3; cancer antigen 15-3; carcinoma-associated mucin; CD227; EMA; episialin; H23 antigen; H23AG; KL-6; krebs von den Lungen-6; MAM6; MCD; MCKD; MCKD1; MUC-1; MUC-1/SEC; MUC-1/X; MUC1/ZD; mucin 1, transmembrane; mucin-1; peanut-reactive urinary mucin; PEM; PEMT; polymorphic epithelial mucin; PUM; tumor associated epithelial mucin; tumor-associated epithelial membrane antigen
- HostMouse
- IsotypeIgG2b
- Protein IDP15941
- Protein NameMucin-1
- Scientific DescriptionThis MAb reacts with MUC1, a large transmembrane glycoprotein expressed on the ductal surface of normal glandular epithelia. It is used as tracer agent in CA15. 3 assays. The extracellular domain of MUC1 largely consists of a highly conserved, O-glycosylated 20 amino acids tandem repeat which can occur 30-100 times per molecule depending on the length of the allele involved. In the vast majority of human carcinomas this protein is up-regulated and poorly glycosylated and appears on the cell surface in a non-polarized fashion. The dominant epitope of this MAb involves both amino acids as well as sugar moieties. Its epitope is destroyed by desialylation i. e. treatment with Neuraminidase. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- SourceAnimal
- ReactivityBovine, Human, Mouse
- Storage Instruction2°C to 8°C
- UNSPSC12352203