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ProductsBack/MUC16 / CA125 (Ovarian Carcinoma Marker)(500000000000), CF594 conjugate, 0.1mg/mL [26628-22-8]
MUC16 / CA125 (Ovarian Carcinoma Marker)(500000000000), CF594 conjugate, 0.1mg/mL [26628-22-8]

MUC16 / CA125 (Ovarian Carcinoma Marker)(500000000000), CF594 conjugate, 0.1mg/mL [26628-22-8]

Research Use Only
BNC942624
Biotium
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityBovine, Human, Mouse
TargetMUC16
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Overview

  • Supplier
    Biotium
  • Product Name
    MUC16 / CA125 (Ovarian Carcinoma Marker)(500000000000), CF594 conjugate, 0.1mg/mL
  • Delivery Days Customer
    9
  • Applications
    ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    #5E11
  • Concentration
    0.1 mg/ml
  • Conjugate
    Other Conjugate
  • Gene ID94025
  • Target name
    MUC16
  • Target description
    mucin 16, cell surface associated
  • Target synonyms
    CA125; CA125 ovarian cancer antigen; cancer antigen 125; mucin-16; ovarian cancer-related tumor marker CA125; ovarian carcinoma antigen CA125
  • Host
    Mouse
  • Isotype
    IgG1
  • Protein IDQ8WXI7
  • Protein Name
    Mucin-16
  • Scientific Description
    The mucins are a family of highly glycosylated, secreted proteins with a basic structure consisting of a variable number of tandem repeats (VNTRs). Membrane-associated and secretory Mucins are high molecular weight glycoproteins of the glycocalyx (polysaccharide biofilm) that protects mucosal epithelium from particulate matter and microorganisms. Epithelial Mucins are large, secreted and cell surface glycoproteins crucial for adhesion modulation, signaling and epithelial cell protection. The number of repeats is highly polymorphic and varies among different alleles. The Mucin family consists of Mucins 1-4, Mucin 5 (AC and B), Mucins 6-8, Mucins 11-13 and Mucins 15-17. The Mucin 16 protein (also commonly referred to as CA125), encoded for by the gene MUC16, is a very high molecular weight tumor antigen consisting of three domains: a carboxy terminal domain, an extracellular domain and an amino terminal domain. Mucin 16, an ovarian cancer-associated antigen, is used as a marker to monitor the progress of epithelial ovarian cancer. It is a hydrophilic membrane-associated protein that may be involved in vitamin A functions. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
  • Source
    Animal
  • Reactivity
    Bovine, Human, Mouse
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203