
Drosophila tissue extract (50 μg) was separated by 10% SDS-PAGE, and the membrane was blotted with MUL1 antibody (GTX112673) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
MUL1 antibody
GTX112673
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityDrosophila, Human
TargetMUL1
Overview
- SupplierGeneTex
- Product NameMUL1 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.97 mg/ml
- ConjugateUnconjugated
- Gene ID79594
- Target nameMUL1
- Target descriptionmitochondrial E3 ubiquitin protein ligase 1
- Target synonymsC1orf166, GIDE, MAPL, MULAN, RNF218, mitochondrial ubiquitin ligase activator of NFKB 1, E3 SUMO-protein ligase MUL1, E3 ubiquitin ligase, E3 ubiquitin-protein ligase MUL1, RING-type E3 ubiquitin transferase NFKB 1, growth inhibition and death E3 ligase, mitochondria-anchored protein ligase, mitochondrial E3 ubiquitin ligase 1, mitochondrial ubiquitin ligase activator of NF-kB, mitochondrial-anchored protein ligase, protein Hades, putative NF-kappa-B-activating protein 266, ring finger protein 218
- HostRabbit
- IsotypeIgG
- Protein IDQ969V5
- Protein NameMitochondrial ubiquitin ligase activator of NFKB 1
- Scientific DescriptionE3 ubiquitin-protein ligase that plays a role in the control of mitochondrial morphology. Promotes mitochondrial fragmentation and influences mitochondrial localization. Inhibits cell growth. When overexpressed, activates JNK through MAP3K7/TAK1 and induces caspase-dependent apoptosis. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.
- ReactivityDrosophila, Human
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Farmer T, Reinecke JB, Xie S, et al. Control of mitochondrial homeostasis by endocytic regulatory proteins. J Cell Sci. 2017,130(14):2359-2370. doi: 10.1242/jcs.204537Read this paper





