MUL1 antibody
GTX112673
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityDrosophila, Human
TargetMUL1
Overview
- SupplierGeneTex
- Product NameMUL1 antibody
- Delivery Days Customer9
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1.88 mg/ml
- ConjugateUnconjugated
- Gene ID79594
- Target nameMUL1
- Target descriptionmitochondrial E3 ubiquitin protein ligase 1
- Target synonymsC1orf166; E3 SUMO-protein ligase MUL1; E3 ubiquitin ligase; E3 ubiquitin-protein ligase MUL1; GIDE; growth inhibition and death E3 ligase; MAPL; mitochondria-anchored protein ligase; mitochondrial E3 ubiquitin ligase 1; mitochondrial ubiquitin ligase activator of NF-kB; mitochondrial ubiquitin ligase activator of NFKB 1; mitochondrial-anchored protein ligase; MULAN; protein Hades; putative NF-kappa-B-activating protein 266; ring finger protein 218; RING-type E3 ubiquitin transferase NFKB 1; RNF218
- HostRabbit
- IsotypeIgG
- Scientific DescriptionE3 ubiquitin-protein ligase that plays a role in the control of mitochondrial morphology. Promotes mitochondrial fragmentation and influences mitochondrial localization. Inhibits cell growth. When overexpressed, activates JNK through MAP3K7/TAK1 and induces caspase-dependent apoptosis. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.
- ReactivityDrosophila, Human
- Storage Instruction2°C to 8°C,-20°C or -80°C
- UNSPSC12352203
References
- Control of mitochondrial homeostasis by endocytic regulatory proteins. Farmer T et al., 2017 Jul 15, J Cell SciRead more