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MUL1 antibody

Research Use Only
GTX112673
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityDrosophila, Human
TargetMUL1
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Overview

  • Supplier
    GeneTex
  • Product Name
    MUL1 antibody
  • Delivery Days Customer
    9
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1.88 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID79594
  • Target name
    MUL1
  • Target description
    mitochondrial E3 ubiquitin protein ligase 1
  • Target synonyms
    C1orf166; E3 SUMO-protein ligase MUL1; E3 ubiquitin ligase; E3 ubiquitin-protein ligase MUL1; GIDE; growth inhibition and death E3 ligase; MAPL; mitochondria-anchored protein ligase; mitochondrial E3 ubiquitin ligase 1; mitochondrial ubiquitin ligase activator of NF-kB; mitochondrial ubiquitin ligase activator of NFKB 1; mitochondrial-anchored protein ligase; MULAN; protein Hades; putative NF-kappa-B-activating protein 266; ring finger protein 218; RING-type E3 ubiquitin transferase NFKB 1; RNF218
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    E3 ubiquitin-protein ligase that plays a role in the control of mitochondrial morphology. Promotes mitochondrial fragmentation and influences mitochondrial localization. Inhibits cell growth. When overexpressed, activates JNK through MAP3K7/TAK1 and induces caspase-dependent apoptosis. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.
  • Reactivity
    Drosophila, Human
  • Storage Instruction
    2°C to 8°C,-20°C or -80°C
  • UNSPSC
    12352203

References

  • Control of mitochondrial homeostasis by endocytic regulatory proteins. Farmer T et al., 2017 Jul 15, J Cell Sci
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