Multitarget AD inhibitor-1 [2205015-77-4]

TargetMol Chemicals

Multitarget AD inhibitor-1 [2205015-77-4]

999

2205015-77-4

Chemical

Research Use Only

Multitarget AD inhibitor-1

C29H38N2O

430.636

Multitarget AD inhibitor-1 is a reversible and selective inhibitor of butyrylcholinesterase (BuChE) with IC50 values of 7.22 microM for human BuChE (hBuChE) and 1.55 microM for equine serum BuChE (eqBuChE). It also exhibits inhibitory activity towards beta-secretase (IC50 41.60 microM), amyloid beta aggregation (IC50 3.09 microM), and tau aggregation. As a diphenylpropylamine derivative, Multitarget AD inhibitor-1 is promising for research into multifunctional, disease-modifying treatments for Alzheimers disease.

3 years

CC(C)(C)c1cccc(CNCC(O)CNCCC(c2ccccc2)c2ccccc2)c1

-20°C

51202000