Murine BD3 protein

Biorbyt

Murine BD3 protein

16

Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Further dilutions should be made in appropriate buffered solutions.

Other Application

HPLC, SDS-PAGE

Research Use Only

Unconjugated

>95%

Beta defensin 3, also known as BD3 and DEFB3, is a membrane active cationic peptide that functions in inflammation and innate immune responses and coded by Defb 3 gene on chromosome 8 in mouse. There are at least 30 beta-defensins which are distinguished from alpha-defensins by the connectivity pattern of their three intramolecular disulfide bonds. BD3 is widely expressed among epithelial tissues, notably by keratinocytes and airway epithelial cells. It is upregulated in response to proinflammatory cytokines, microbial and viral infections, and at the edges of skin wounds. BD3 induction in osteoarthritis chondrocytes promotes MMP1 and 13 productions and inhibits TIMP1 and 2 expressions.

E.coli

-20°C,2°C to 8°C

12352202