IHC-P analysis of human skeletal muscle tissue using GTX25619 MUSK antibody. Right : Primary antibody Left : Negative control without primary antibody Antigen retrieval : heat induced antigen retrieval was performed using 10mM sodium citrate (pH 6.0) buffer for 10 minutes using a microwave Permeabilization : TBS/0.025% Triton Dilution : 1:20
IHC-P analysis of human skeletal muscle tissue using GTX25619 MUSK antibody. Right : Primary antibody Left : Negative control without primary antibody Antigen retrieval : heat induced antigen retrieval was performed using 10mM sodium citrate (pH 6.0) buffer for 10 minutes using a microwave Permeabilization : TBS/0.025% Triton Dilution : 1:20
MUSK antibody
GTX25619
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetMusk
Overview
- SupplierGeneTex
- Product NameMUSK antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:1000. ICC/IF: 1:20-1:100. IHC-P: 1:20-1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID18198
- Target nameMusk
- Target descriptionmuscle, skeletal, receptor tyrosine kinase
- Target synonymsMdk4; Mlk; muscle localized kinase 2; muscle, skeletal receptor tyrosine-protein kinase; muscle-specific kinase receptor; muscle-specific tyrosine-protein kinase receptor; Ns; Nsk1; Nsk2; Nsk3
- HostRabbit
- IsotypeIgG
- Protein IDQ61006
- Protein NameMuscle, skeletal receptor tyrosine-protein kinase
- Scientific DescriptionThis gene encodes a member of the protein tyrosine kinase family. The encoded protein is a type 1 receptor-like protein located in muscle membrane that is activated by the heparan sulfate proteoglycan agrin released by nerve cells. The encoded protein activates signaling cascades responsible for multiple aspects of motor neuron and muscle development, including organization of the postsynaptic membrane, synaptic gene transcription, patterning of skeletal muscle, anchoring of acetylcholinesterase, and guidance of motor axons. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Inhibiting Matrix Metalloproteinases Protects Evoked Electromyography Amplitudes and Muscle Tension in the Orbicularis Oris Muscle in a Rat Model of Facial Nerve Injury.Read more