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ProductsBack/MutS Protein Homolog 2(MSH2) Monoclonal Antibody

MutS Protein Homolog 2(MSH2) Monoclonal Antibody

RD6750
Reddot Biotech
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetMSH2
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Overview

  • Supplier
    Reddot Biotech
  • Product Name
    MutS Protein Homolog 2(MSH2) Monoclonal Antibody
  • Delivery Days Customer
    5
  • Applications
    ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Concentration
    100 ug/ml
  • Gene ID4436
  • Target name
    MSH2
  • Target description
    mutS homolog 2
  • Target synonyms
    COCA1; DNA mismatch repair protein Msh2; DNA mismatch repair protein Msh2 transcript; FCC1; hMSH2; HNPCC; HNPCC1; LCFS2; MMRCS2; mutS homolog 2, colon cancer, nonpolyposis type 1
  • Host
    Mouse
  • Scientific Description
    DNA mismatch repair (MMR) system is composed of enzyme molecules that specifically repair DNA base mismatch. The existence of this system can ensure the integrity and stability of genetic material, avoid the mutation of genetic material, and ensure the high fidelity of DNA replication. It is composed of hMLH1, hMSH2, hpms1, hPMS2 and other genes. HMSH2 is located in human chromosome 2p21-22, encoding a protein composed of 934 aa. The mutation of hMSH2 gene occurs in sporadic colorectal cancer. The mutation of microsatellite hMSH2 gene is related to 50% of familial and non-familial polyposis colorectal cancer (HNPCC).
  • UNSPSC
    12352203