MUTYH Polyclonal Antibody

Reddot Biotech

MUTYH Polyclonal Antibody

5

Western Blot, ELISA

Research Use Only

Polyclonal

0.4 mg/ml

Unconjugated

MUTYH

mutY DNA glycosylase

A/G-specific adenine DNA glycosylase; adenine DNA glycosylase; mutY homolog; mutY-like protein; MYH

Rabbit

IgG

This gene encodes a DNA glycosylase involved in oxidative DNA damage repair. The enzyme excises adenine bases from the DNA backbone at sites where adenine is inappropriately paired with guanine, cytosine, or 8-oxo-7,8-dihydroguanine, a major oxidatively damaged DNA lesion. The protein is localized to the nucleus and mitochondria. Mutations in this gene result in heritable predisposition to colon and stomach cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

Human

-20°C

12352203