Muvalaplin

MedChem Express

Muvalaplin

10

Research Use Only

99.96

C42H54N4O6

710.90

Muvalaplin (LY3473329) is an orally active, selective small molecule inhibitor of lipoprotein (a) ( Lp (a) ) that disrupts the initial non-covalent interaction between apo(a) and apoB100, preventing the disulphide bond and Lp(a) formation. Muvalaplin reduces the levels of Lp (a) in transgenic mice and in cynomolgus monkeys [1] [2] [3] [4] [5] .

OC([C@H]([C@H]1CCNC1)CC2=CC(CN(CC3=CC(C[C@@H]([C@H]4CCNC4)C(O)=O)=CC=C3)CC5=CC(C[C@@H]([C@H]6CCNC6)C(O)=O)=CC=C5)=CC=C2)=O

-20°C,2°C to 8°C

12352200