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Western blot analysis of extracts from HL60, MCF and K562 cells using Myc(Ab-358) Antibody.
Western blot analysis of extracts from HL60, MCF and K562 cells using Myc(Ab-358) Antibody.
Western blot analysis of extracts from HL60, MCF and K562 cells using Myc(Ab-358) Antibody.

MYC (Ab-358) Antibody

CSB-PA930453
Cusabio
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetMYC
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Overview

  • Supplier
    Cusabio
  • Product Name
    MYC (Ab-358) Antibody
  • Delivery Days Customer
    20
  • Applications
    Western Blot, ELISA, ImmunoHistoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID4609
  • Target name
    MYC
  • Target description
    MYC proto-oncogene, bHLH transcription factor
  • Target synonyms
    avian myelocytomatosis viral oncogene homolog; bHLHe39; class E basic helix-loop-helix protein 39; c-Myc; MRTL; myc proto-oncogene protein; MYCC; myc-related translation/localization regulatory factor; proto-oncogene c-Myc; transcription factor p64; v-myc avian myelocytomatosis viral oncogene homolog; v-myc myelocytomatosis viral oncogene homolog
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP01106
  • Protein Name
    Myc proto-oncogene protein
  • Scientific Description
    Myc proto-oncogene encodes nuclear DNA-binding phosphoproteins that are involved in the regulation of gene expression and DNA replication during cell growth and differentiation. Myc encodes a protein of 65 kDa which is expressed in almost all normal and transformed cells. The expression correlates with the proliferation state of the cells. Transcription is repressed in quiescent or terminally differentiated cells. Expression of Myc is generally induced after mitogenic stimulation of cells or serum induction. Myc therefore is an important positive regulator of cell growth and proliferation. Myc has been demonstrated also to be a potent inducer of apoptosis when expressed in the absence of serum or growth factors. Apoptosis may serve also as a protective mechanism to prevent tumorigenicity elicited by deregulated Myc expression. Sequences of the Myc oncogene have been highly conserved throughout evolution, from Drosophila to vertebrates Baudino T A, et al. (2001) Mol Cell Biol. 21: 691-702. Blackwood E M, et al. (1991) Science. 251:1211-1217. Henriksson M, et al. (1996) Adv Cancer Res. 68: 109-182. Grandori C, et al. (2000) Annu Rev Cell Dev Biol. 16: 653-699.
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C
  • UNSPSC
    12352203