ProductsBack/Myelin PLP antibody

In this tissue section through an e13 mouse brain, PLP (green staining) can be seen in immature oligodendrocytes of white matter tracts. DAPI (blue staining) allows visualization of nuclei.

Myelin PLP antibody

GTX85465

ApplicationsImmunoFluorescence, ImmunoCytoChemistry, ImmunoHistoChemistry

DownloadDatasheet

Product group Antibodies

TargetPLP1

Overview

Supplier
GeneTex
Product Name
Myelin PLP antibody
Delivery Days Customer
9
Application Supplier Note
Recommended starting dilutions: For IHC/IF: Use at 1:1000 - 1:2000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.
Applications
ImmunoFluorescence, ImmunoCytoChemistry, ImmunoHistoChemistry
Certification
Research Use Only
Clonality
Polyclonal
Concentration
100 ug/ml
Conjugate
Unconjugated
Gene ID5354
Target name
PLP1
Target description
proteolipid protein 1
Target synonyms
GPM6C; HLD1; lipophilin; major myelin proteolipid protein; MMPL; myelin proteolipid protein; PLP; PLP/DM20; PMD; SPG2
Host
Chicken
Isotype
IgY
Protein IDP60201
Protein Name
Myelin proteolipid protein
Scientific Description
This gene encodes a transmembrane proteolipid protein that is the predominant component of myelin. The encoded protein may play a role in the compaction, stabilization, and maintenance of myelin sheaths, as well as in oligodendrocyte development and axonal survival. Mutations in this gene cause Pelizaeus-Merzbacher disease and spastic paraplegia type 2. Alternatively splicing results in multiple transcript variants, including the DM20 splice variant. [provided by RefSeq, Feb 2015]
Storage Instruction
2°C to 8°C
UNSPSC
12352203

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