In this tissue section through an e13 mouse brain, PLP (green staining) can be seen in immature oligodendrocytes of white matter tracts. DAPI (blue staining) allows visualization of nuclei.
In this tissue section through an e13 mouse brain, PLP (green staining) can be seen in immature oligodendrocytes of white matter tracts. DAPI (blue staining) allows visualization of nuclei.
Myelin PLP antibody
GTX85465
Overview
- SupplierGeneTex
- Product NameMyelin PLP antibody
- Delivery Days Customer9
- Antibody Specificityproteolipid protein 1
- Application Supplier NoteRecommended starting dilutions: For IHC/IF: Use at 1:1000 - 1:2000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.
- Concentration100 ug/ml
- FormulationLiquid
- Gene ID5354
- Target namePLP1
- Target descriptionproteolipid protein 1
- Target synonymsGPM6C; HLD1; lipophilin; major myelin proteolipid protein; MMPL; myelin proteolipid protein; PLP; PLP/DM20; PMD; SPG2
- Protein IDP60201
- Protein NameMyelin proteolipid protein
- Scientific DescriptionThis gene encodes a transmembrane proteolipid protein that is the predominant component of myelin. The encoded protein may play a role in the compaction, stabilization, and maintenance of myelin sheaths, as well as in oligodendrocyte development and axonal survival. Mutations in this gene cause Pelizaeus-Merzbacher disease and spastic paraplegia type 2. Alternatively splicing results in multiple transcript variants, including the DM20 splice variant. [provided by RefSeq, Feb 2015]
- Storage Instruction2°C to 8°C
- UNSPSC12352203