Myosin Light chain antibody [MY-21]
![Research Use Only](static/images/certificates/ruo.jpg)
GTX11082
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
Product group Antibodies
ReactivityBovine, Chicken, Human, Porcine, Rabbit
Overview
- SupplierGeneTex
- Product NameMyosin Light chain antibody [MY-21]
- Delivery Days Customer10
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDMY-21
- HostMouse
- IsotypeIgM
- Scientific DescriptionContractile proteins are ubiquitous in eukaryotic cells. Their presence is related to motile functions. The two major cytoskeletal proteins implicated in cell motility are actin and myosin. Numerous investigators have shown that actin and myosin are constituents of many cell types and are involved in a myriad of cellular processes including locomotion, secretion, cytoplasmic streaming, phagocytosis, and cytokinesis. Myosin is a 500,000 dalton protein known to interact with identical heavy chains (200,000 daltons each) and four light chains (15,000-20,000 daltons). Myosin molecules consist of two major regions: tail (rod) and head regions. Myosin has three major biological functions:1. Myosin molecules spontaneously assemble into filaments in solutions of physiologic ionic strength and pH. Thick filaments consist mainly of myosin molecules.2. Myosin is an enzyme (ATPase) and its activity is the immediate source of the free energy that drives muscle contraction.3. Myosin binds to the polymerized form of actin, the major constituent of the thin filament.Myosin can be viewed in immunofluorescent microscopy enabling the delineation of the intracellular organization of proteins that are in the form of a supramolecular structure.
- ReactivityBovine, Chicken, Human, Porcine, Rabbit
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- Autologous Adipose-Derived Tissue Matrix Part I: Biologic Characteristics. Schendel SA, 2017 Oct 1, Aesthet Surg JRead more