Myosin Light chain antibody [MY-21]

GeneTex

Myosin Light chain antibody [MY-21]

9

ICC/IF: 1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoFluorescence, Western Blot, ImmunoCytoChemistry

Research Use Only

Monoclonal

MY-21

Unconjugated

Liquid

MYL1

myosin, light chain 1, alkali; skeletal, fast

alkali myosin light chain 1; alkali myosin light chain 3; light polypeptide 1; MLC; MLC-1; MLC-3; myosin a1; myosin light chain 1, skeletal muscle isoform; myosin light chain 1f; myosin light chain 3f; myosin light chain A1; myosin light chain A2; myosin light chain alkali 1; myosin light chain alkali 2; myosin, light polypeptide 1, alkali; skeletal, fast; skeletal-muscle myosin L-1 light chain; skeletal-muscle myosin L-4 light chain

Mouse

IgM

Myosin light chain 3, skeletal muscle isoform

Contractile proteins are ubiquitous in eukaryotic cells. Their presence is related to motile functions. The two major cytoskeletal proteins implicated in cell motility are actin and myosin. Numerous investigators have shown that actin and myosin are constituents of many cell types and are involved in a myriad of cellular processes including locomotion, secretion, cytoplasmic streaming, phagocytosis, and cytokinesis. Myosin is a 500,000 dalton protein known to interact with identical heavy chains (200,000 daltons each) and four light chains (15,000-20,000 daltons). Myosin molecules consist of two major regions: tail (rod) and head regions. Myosin has three major biological functions:1. Myosin molecules spontaneously assemble into filaments in solutions of physiologic ionic strength and pH. Thick filaments consist mainly of myosin molecules.2. Myosin is an enzyme (ATPase) and its activity is the immediate source of the free energy that drives muscle contraction.3. Myosin binds to the polymerized form of actin, the major constituent of the thin filament.Myosin can be viewed in immunofluorescent microscopy enabling the delineation of the intracellular organization of proteins that are in the form of a supramolecular structure.

Bovine, Chicken, Human, Porcine, Rabbit

-20°C or -80°C,2°C to 8°C

12352203