N-563
HY-100751
Overview
- SupplierMedChem Express
- Product NameN-563 [140686-92-6]
- Delivery Days Customer10
- CAS Number140686-92-6
- Estimated Purity98.0
- Molecular FormulaC15H29N5O5
- Molecular Weight359.42
- Scientific DescriptionN-563 is an analogue of deoxyspergualin with an immunostimulating activity,it promotes resistance to Candida albicans infection in mice. In vivo: The protective effect of the N-563 against C. albicans infection was investigated in normal and immunosuppressed mice. In normal mice, N-563 treatment at 10 mg/kg for 3 days prior to infection significantly prolonged the survival time. In immunosuppressed mice treated with a single dose of cyclophosphamide 4 days prior to infection, N-563 at 3 and 10 mg/kg for 3 days prior to infection also significantly prolonged the survival time of mice. In addition, it augmented the phagocytic activity of neutrophils and enhanced the delayed type hypersensitivity reaction against C. albicans. Coincidentally, N-563 appeared to protect against secondary infection with C. albicans in the delayed type hypersensitivity-positive mice.[1] N-563 was dissolved in physiological saline and filtered through a Millipore filter (0.22microm).[1]
- SMILESO=C(NCCC(O)=O)CC(O)CNC(CCCCCCNC(N)=N)=O
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200