Bio-Connect

N-563

HY-100751
MedChem Express
CAS Number140686-92-6
Product group Chemicals
Estimated Purity98.0
Molecular Weight359.42
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    MedChem Express
  • Product Name
    N-563 [140686-92-6]
  • Delivery Days Customer
    10
  • CAS Number
    140686-92-6
  • Estimated Purity
    98.0
  • Molecular Formula
    C15H29N5O5
  • Molecular Weight
    359.42
  • Scientific Description
    N-563 is an analogue of deoxyspergualin with an immunostimulating activity,it promotes resistance to Candida albicans infection in mice. In vivo: The protective effect of the N-563 against C. albicans infection was investigated in normal and immunosuppressed mice. In normal mice, N-563 treatment at 10 mg/kg for 3 days prior to infection significantly prolonged the survival time. In immunosuppressed mice treated with a single dose of cyclophosphamide 4 days prior to infection, N-563 at 3 and 10 mg/kg for 3 days prior to infection also significantly prolonged the survival time of mice. In addition, it augmented the phagocytic activity of neutrophils and enhanced the delayed type hypersensitivity reaction against C. albicans. Coincidentally, N-563 appeared to protect against secondary infection with C. albicans in the delayed type hypersensitivity-positive mice.[1] N-563 was dissolved in physiological saline and filtered through a Millipore filter (0.22microm).[1]
  • SMILES
    O=C(NCCC(O)=O)CC(O)CNC(CCCCCCNC(N)=N)=O
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200