N-Acetylgalactosaminyltransferase 4

MedChem Express

N-Acetylgalactosaminyltransferase 4

5

Research Use Only

N-Acetylgalactosaminyltransferase 4 (GALNT4) is a glycosyltransferase capable of inhibiting the activation of ASK1. By directly binding to ASK1, N-Acetylgalactosaminyltransferase 4 suppresses its N-terminal dimerization and subsequent phosphorylation, leading to robust inactivation of downstream JNK/p38 and NF-kappaB signals, and thereby improving the prognosis of liver surgery[1].

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