N-(Azido-PEG3)-N-(PEG2-NH-Boc)-PEG3-acid [2183440-74-4]

MedChem Express

N-(Azido-PEG3)-N-(PEG2-NH-Boc)-PEG3-acid [2183440-74-4]

10

2183440-74-4

Research Use Only

98.07

C29H55N5O13

681.77

N-(Azido-PEG3)-N-(PEG2-NH-Boc)-PEG3-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. N-(Azido-PEG3)-N-(PEG2-NH-Boc)-PEG3-acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

O=C(OC(C)(C)C)NCCOCCOCCC(N(CCOCCOCCOCCN=[N+]=[N-])CCOCCOCCOCCC(O)=O)=O

-20°C,2°C to 8°C

41115800