N-Cadherin antibody [GC-4]
GTX11340
ApplicationsElectron Microscopy, Flow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
Product group Antibodies
ReactivityChicken, Human, Mouse, Rabbit, Rat
TargetCDH2
Overview
- SupplierGeneTex
- Product NameN-Cadherin antibody [GC-4]
- Delivery Days Customer9
- Application Supplier NoteWB: 1:100. IHC-Fr: 1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsElectron Microscopy, Flow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDGC-4
- ConjugateUnconjugated
- Gene ID414745
- Target nameCDH2
- Target descriptioncadherin 2
- Target synonymscadherin 2, type 1, N-cadherin (neuronal); cadherin-2; N-cadherin; neural cadherin; neural calcium-dependent cell adhesion molecule
- HostMouse
- IsotypeIgG1
- Protein IDP10288
- Protein NameCadherin-2
- Scientific DescriptionMonoclonal Anti-N Cadherin/ACAM may be used for the localization of a 135 kDa receptor of the intercellular adherens junction in immunofluorescent microscopy, electron microscopy, and immunoblotting. This antibody can also be used to study the mechanism of adhesion and interaction of cultured cells and cells in tissues.Monoclonal Anti-NCadherin/ACAM stains a large variety of intercellular junctions formed by chicken fibroblastic and epithelial cells in culture. In adult mammals, the antibody stains predominantly heart and lens tissue and also stains a large variety of embryonic tissue. By double labelling, this antibody appears to localize vinculin and actin-rich intercellular contacts and is absent from cellular matrix attachment sites.
- ReactivityChicken, Human, Mouse, Rabbit, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Lack of evidence that hematopoietic stem cells depend on N-cadherin-mediated adhesion to osteoblasts for their maintenance. Kiel MJ et al., 2007 Aug 16, Cell Stem CellRead more
- N-cadherin-mediated intercellular interactions promote survival and migration of melanoma cells. Li G et al., 2001 May 1, Cancer ResRead more