N-Desethyl Sunitinib-d5 (hydrochloride)

MedChem Express

N-Desethyl Sunitinib-d5 (hydrochloride)

5

Research Use Only

C20H19D5ClFN4O2

411.91

N-Desethyl Sunitinib-d5 (hydrochloride) is a deuterated labeled N-Desethyl Sunitinib [1] . N-Desethyl Sunitinib (SU-12662) is a metabolite of sunitinib. Sunitinib is a potent, ATP-competitive VEGFR , PDGFRbeta and KIT inhibitor with K i values of 2, 9, 17, 8 and 4 nM for VEGFR -1, -2, -3, PDGFRbeta and KIT, respectively [2] .

O=C(/C(C1=C2)=C/C3=C(C(C(NCCNC([2H])([2H])C([2H])([2H])[2H])=O)=C(N3)C)C)NC1=CC=C2F.Cl

12352200