N-Formyl-Met-Leu-Phe-Lys [67247-11-4]

TargetMol Chemicals

N-Formyl-Met-Leu-Phe-Lys [67247-11-4]

9

67247-11-4

Chemical

Research Use Only

N-Formyl-Met-Leu-Phe-Lys

99.70%

C27H43N5O6S

565.73

N-Formyl-Met-Leu-Phe-Lys (fMLFK) is a peptide that acts as a potent and selective agonist of FPR1, with EC50s of 3.5 nM for FPR1, 6.7 microM for FPR2, and 0.88 microM for FPR2-D2817.32G. This chemotactic peptide binds specifically to receptors on leukocyte membranes and its uptake can contribute to the quantitative assessment of neutrophils in localized inflammatory processes, independent of associated edema formation or microcirculatory compromise.

3 years

[C@@H](CC1=CC=CC=C1)(NC([C@@H](NC([C@H](CCSC)NC=O)=O)CC(C)C)=O)C(N[C@@H](CCCCN)C(O)=O)=O

-20°C

12352200