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N-Palmitoyl Glycine [2441-41-0]

N-Palmitoyl Glycine [2441-41-0]

T37219
TargetMol Chemicals
CAS Number2441-41-0
Product group Chemicals
Molecular Weight313.48
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    N-Palmitoyl Glycine [2441-41-0]
  • Delivery Days Customer
    14
  • CAS Number
    2441-41-0
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    N-Palmitoyl Glycine
  • Molecular Formula
    C18H35NO3
  • Molecular Weight
    313.48
  • Scientific Description
    The acyl amides are a family of endogenous lipids that act as potent modulators of pain and inflammation. The best characterized members of this family are the arachidonoyl amides, which includes N-arachidonoyl ethanolamide (AEA; anandamide). N-palmitoyl glycine (PalGly) contains an 18-carbon saturated fatty acid that is amide-linked to glycine and is structurally similar to the phospholipid-derived N-acyl ethanolamines. Endogenously produced in rat skin and spinal cord, PalGly is present in 100-fold greater amounts in skin and 3-fold greater in brain compared to AEA. Injection of 0.43 microg PalGly in rat hindpaw inhibits heat-induced firing of nociceptive neurons in rat dorsal horn. PalGly treatment induces transient calcium influx in native dorsal root ganglion (DRG) cells and in the PTX-sensitive, DRG-like cell line F-11 (EC50 = 5.5 microM).
  • Shelf life instruction
    3 years
  • SMILES
    CCCCCCCCCCCCCCCC(=O)NCC(O)=O
  • Storage Instruction
    -20°C
  • UNSPSC
    12352209

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