N6F11

AbMole BioScience

N6F11

9

851398-76-0

Chemical

Research Use Only

C13H8Cl2N2OS

311.19

N6F11 is a novel ferroptosis inducer that selectively triggers the ubiquitination degradation of GPX4 by binding to the specific structural domain of TRIM25, a ubiquitinated E3 ligase, which is expressed in tumor cells, leading to ferroptosis in cancer cells.

ClCC1=NC(=O)C2=C(N1)C=C(S2)C3=CC=C(Cl)C=C3

12352200