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NAD Nucleotidase (H. influenzae) (rec.)

Research Use Only
AG-40T-0110
AdipoGen Life Sciences
Product group Molecular Biology
Price on request
Packing Size
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Overview

  • Supplier
    AdipoGen Life Sciences
  • Product Name
    NAD Nucleotidase (H. influenzae) (rec.)
  • Delivery Days Customer
    10
  • Certification
    Research Use Only
  • Scientific Description
    NadN (NAD nucleotidase) is a periplasmic enzyme from Haemophilus influenzae, a major pathogen of the respiratory tract in humans that has developed the capability to exploit host NAD(P) for its nicotinamide dinucleotide requirement. NadN plays a central role by degrading NAD into adenosine and NR (nicotinamide riboside), NMN to nicotinamide riboside and AMP to adenosine. It shows a broad substrate specificity, recognizing either mono- or di-nucleotide nicotinamides and different adenosine phosphates with a maximal activity on 5-adenosine monophosphate. It can be used as an economically alternative to produce NR (nicotinamide riboside). Catalytic activity: NAD=AMP + NMN=Ade+NR+PPi - AMP=Ade+Pi - NMN=NR+Pi - Protein. Full-length NAD 5-nucleotidase (Haemophilus influenzae) without the signal peptide corresponding to the first 26 aa. Source: E. coli. Endotoxin content: N/A. Liquid. In 5mM KH2PO4, pH 6.8 containing 100mM TRIS-HCl (pH 8.5) and 10mM MgCl2. Purity: >98% (SDS-PAGE). NadN (NAD nucleotidase) is a periplasmic enzyme from Haemophilus influenzae, a major pathogen of the respiratory tract in humans that has developed the capability to exploit host NAD(P) for its nicotinamide dinucleotide requirement. NadN plays a central role by degrading NAD into adenosine and NR (nicotinamide riboside), NMN to nicotinamide riboside and AMP to adenosine. It shows a broad substrate specificity, recognizing either mono- or di-nucleotide nicotinamides and different adenosine phosphates with a maximal activity on 5-adenosine monophosphate. It can be used as an economically alternative to produce NR (nicotinamide riboside). Catalytic activity: NAD=AMP + NMN=Ade+NR+PPi - AMP=Ade+Pi - NMN=NR+Pi
  • Storage Instruction
    -20°C,-80°C
  • UNSPSC
    41116133