NAD Nucleotidase (H. influenzae) (rec.)
AG-40T-0110
Product group Molecular Biology
Overview
- SupplierAdipoGen Life Sciences
- Product NameNAD Nucleotidase (H. influenzae) (rec.)
- Delivery Days Customer10
- CertificationResearch Use Only
- Scientific DescriptionNadN (NAD nucleotidase) is a periplasmic enzyme from Haemophilus influenzae, a major pathogen of the respiratory tract in humans that has developed the capability to exploit host NAD(P) for its nicotinamide dinucleotide requirement. NadN plays a central role by degrading NAD into adenosine and NR (nicotinamide riboside), NMN to nicotinamide riboside and AMP to adenosine. It shows a broad substrate specificity, recognizing either mono- or di-nucleotide nicotinamides and different adenosine phosphates with a maximal activity on 5-adenosine monophosphate. It can be used as an economically alternative to produce NR (nicotinamide riboside). Catalytic activity: NAD=AMP + NMN=Ade+NR+PPi - AMP=Ade+Pi - NMN=NR+Pi - Protein. Full-length NAD 5-nucleotidase (Haemophilus influenzae) without the signal peptide corresponding to the first 26 aa. Source: E. coli. Endotoxin content: N/A. Liquid. In 5mM KH2PO4, pH 6.8 containing 100mM TRIS-HCl (pH 8.5) and 10mM MgCl2. Purity: >98% (SDS-PAGE). NadN (NAD nucleotidase) is a periplasmic enzyme from Haemophilus influenzae, a major pathogen of the respiratory tract in humans that has developed the capability to exploit host NAD(P) for its nicotinamide dinucleotide requirement. NadN plays a central role by degrading NAD into adenosine and NR (nicotinamide riboside), NMN to nicotinamide riboside and AMP to adenosine. It shows a broad substrate specificity, recognizing either mono- or di-nucleotide nicotinamides and different adenosine phosphates with a maximal activity on 5-adenosine monophosphate. It can be used as an economically alternative to produce NR (nicotinamide riboside). Catalytic activity: NAD=AMP + NMN=Ade+NR+PPi - AMP=Ade+Pi - NMN=NR+Pi
- Storage Instruction-20°C,-80°C
- UNSPSC41116133