Nagilactone C [24338-53-2]

TargetMol Chemicals

Nagilactone C [24338-53-2]

9

Research Use Only

C19H22O7

362.378

Nagilactone C and phyllanthoside are novel protein synthesis inhibitors, they are specific for the eukaryotic translation apparatus, function in vivo and in vitro, and interfere with translation elongation. Nagilactone C shows high insecticidal activity against second-instar nymphs of Eocanthecona furcellata. Nagilactone C possesses potent antiproliferative activity against human fibrosarcoma and murine colon carcinoma tumor cell lines exhibiting ED50 values of 2.3 and 1.2 microg/ml, respectively.

CC(C)c1oc(=O)cc2c1[C@@H](O)[C@H]1OC(=O)[C@]3(C)C1[C@]2(C)[C@@H]1O[C@@H]1[C@@H]3O

-20°C

12352200