NAI-802 [1426209-02-0]

AdipoGen Life Sciences

NAI-802

10

1426209-02-0

Research Use Only

>75%

C90H141N25O26S4

2117.5

Actagardin-related class II lantibiotic. Antibacterial with improved activity than actagardine against Staphylococcus spp. and Streptococcus spp. Shows significant activity against Gram-positive anaerobic bacteria, such as Clostridium difficile, C. butyricum, C. perfringens and Peptostreptococcus asaccharolyticus. Most probably inhibits cell wall synthesis and consequently bacterial growth by forming a complex with lipid intermediate II (Lipid II), a key intermediate in peptidoglycan biosynthesis. Potential novel antimicrobial agent for the treatment of infections caused by Gram-positive pathogens including resistant strains. - Chemical. CAS: 1426209-02-0. Formula: C90H141N25O26S4. MW: 2117.5. Isolated from Actinoplanes sp. Actagardin-related class II lantibiotic. Antibacterial with improved activity than actagardine against Staphylococcus spp. and Streptococcus spp. Shows significant activity against Gram-positive anaerobic bacteria, such as Clost. difficile, Clostridium butyricum, Clostridium perfringens and Peptostreptococcus asaccharolyticus. Most probably inhibits cell wall synthesis and consequently bacterial growth by forming a complex with lipid intermediate II (Lipid II), a key intermediate in peptidoglycan biosynthesis. Potential novel antimicrobial agent for the treatment of infections caused by Gram-positive pathogens including resistant strains.

O=C(N[C@H](C(N[C@@H](CSC[C@@H](NC([C@@H](N)C)=O)C(N[C@](CO)([H])C(NCC1=O)=O)=O)C(N[C@H]2C(N[C@H](C(N[C@@]3([H])C(N[C@]([C@@H](C)CC)([H])C(N[C@@H](CCC(O)=O)C(N[C@@](C(NCC(N[C@@]([C@@H]4C)([H])C(N[C@H](C(N[C@]([C@@H](C)CC)([H])C(N[C@@](C(N[C@H](C(N[C@H](C(N[C@H](C(O)=O)CCCNC(N)=N)=O)CS4=O)=O)C)=O)([H])CS[C@H]3C)=O)=O)C(C)C)=O)=O)=O)([H])CS[C@H]2C)=O)=O)=O)=O)CC(C)C)=O)=O)=O)C(C)C)[C@](N1)([H])CC5=CNC6=CC=CC=C56

-20°C,2°C to 8°C

12352200