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Naphthofluorescein [61419-02-1]

Naphthofluorescein [61419-02-1]

T36953
TargetMol Chemicals
CAS Number61419-02-1
DownloadMSDS
Product group Chemicals
Estimated Purity99.34%
Molecular Weight432.42
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    Naphthofluorescein [61419-02-1]
  • Delivery Days Customer
    9
  • CAS Number
    61419-02-1
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    Naphthofluorescein
  • Estimated Purity
    99.34%
  • Molecular Formula
    C28H16O5
  • Molecular Weight
    432.42
  • Scientific Description
    Naphthofluorescein (Naphthafluorescein) is a Mint3 inhibitor with potential antitumor and anti-inflammatory activities, inhibits the interaction between HIF-1 and Mint3, inhibits Mint3-dependent HIF-1 activity, and inhibits glycolytic activity in cancer cells and macrophages without showing significant in vitro cytotoxicity or in vivo side effects. Naphthofluorescein is also a fluorescent pH-sensitive probe for functional Cherenkov imaging.
  • Shelf life instruction
    3 years
  • SMILES
    Oc1ccc2c3Oc4c(ccc5cc(O)ccc45)C4(OC(=O)c5ccccc45)c3ccc2c1
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • Pharmacological inhibition of Mint3 attenuates tumour growth, metastasis, and endotoxic shock. Sakamoto T et al., 2021 Oct 7, Commun Biol
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