Naratriptan-d3

MedChem Express

Naratriptan-d3

10

Research Use Only

C17H22D3N3O2S

338.48

Naratriptan-d3 (GR-85548A-d3) is the deuterium labeled Naratriptan (HY-B0197). Naratriptan is a selective 5-HT1B/1D receptor agonist. Naratriptan is peripherally active and has good oral bioavailability, inducing cranial artery vasoconstriction by activating 5-HT1B/1D receptors (EC50=0.11 microM for dog basilar artery). Naratriptan also inhibits trigeminal nerve-mediated dural neurogenic plasma extravasation and reduces sterile inflammation. Naratriptan is mainly used in the research of acute migraine, targeting cranial vascular and neuroinflammatory mechanisms[1][2][3][4][5].

CNS(CCC1=CC=C2NC=C(C3CCN(CC3)C([2H])([2H])[2H])C2=C1)(=O)=O

12352200