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Naratriptan (hydrochloride) (Standard)

HY-B0197AR
MedChem Express
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Naratriptan (hydrochloride) (Standard) [143388-64-1]
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Scientific Description
    Naratriptan (GR-85548A) hydrochloride (Standard) is the analytical standard of Naratriptan hydrochloride (HY-B0197A). This product is intended for research and analytical applications. Naratriptan is a selective 5-HT1B/1D receptor agonist. Naratriptan is peripherally active and has good oral bioavailability, inducing cranial artery vasoconstriction by activating 5-HT1B/1D receptors (EC50=0.11 microM for dog basilar artery). Naratriptan also inhibits trigeminal nerve-mediated dural neurogenic plasma extravasation and reduces sterile inflammation. Naratriptan is mainly used in the research of acute migraine, targeting cranial vascular and neuroinflammatory mechanisms[1][2][3][4].
  • UNSPSC
    41116135