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IHC-Fr analysis of mouse hippocampus tissue using GTX54797 Nav1.2 antibody. Panel A : NaV1.2 (red) is present in dendrites of pyramidal neurons in the CA3 region. Panel B : Staining of?interneurons in the pyramidal layer with mouse anti-Parvalbumin (green) demonstrates the restriction of NaV1.2 to dendrites (arrows) extending from the pyramidal layer (P). Panel C : Confocal merge of panels A and B.
IHC-Fr analysis of mouse hippocampus tissue using GTX54797 Nav1.2 antibody. Panel A : NaV1.2 (red) is present in dendrites of pyramidal neurons in the CA3 region. Panel B : Staining of?interneurons in the pyramidal layer with mouse anti-Parvalbumin (green) demonstrates the restriction of NaV1.2 to dendrites (arrows) extending from the pyramidal layer (P). Panel C : Confocal merge of panels A and B.
IHC-Fr analysis of mouse hippocampus tissue using GTX54797 Nav1.2 antibody. Panel A : NaV1.2 (red) is present in dendrites of pyramidal neurons in the CA3 region. Panel B : Staining of?interneurons in the pyramidal layer with mouse anti-Parvalbumin (green) demonstrates the restriction of NaV1.2 to dendrites (arrows) extending from the pyramidal layer (P). Panel C : Confocal merge of panels A and B.

Nav1.2 antibody

GTX54797
GeneTex
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
DownloadDatasheet
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetScn2a
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Overview

  • Supplier
    GeneTex
  • Product Name
    Nav1.2 antibody
  • Delivery Days Customer
    7
  • Applications
    ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.8 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID24766
  • Target name
    Scn2a
  • Target description
    sodium voltage-gated channel alpha subunit 2
  • Target synonyms
    NachII; Nav1.2; RII/RIIA; RIIA sodium channel protein; RNSCPIIR; SCN; Scn2a1; Scn2a2; ScpII; sodium channel protein type 2 subunit alpha; sodium channel protein type II subunit alpha; sodium channel protein, brain II subunit alpha; sodium channel voltage-gated type II alpha polypeptide; sodium channel, voltage-gated, type 2, alpha 1 polypeptide; sodium channel, voltage-gated, type 2, alpha 1 subunit; sodium channel, voltage-gated, type II, alpha 1; sodium channel, voltage-gated, type II, alpha subunit; voltage-gated sodium channel subunit alpha Nav1.2
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP04775
  • Protein Name
    Sodium channel protein type 2 subunit alpha
  • Scientific Description
    Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit with four repeat domains, each of which is composed of six membrane-spanning segments, and one or more regulatory beta subunits. Voltage-gated sodium channels are responsible for the generation and propagation of action potentials in neurons and muscle. This gene encodes one member of the sodium channel alpha subunit gene family. In humans, variants of this gene are associated with seizure disorders and autism spectrum disorder. Mice homozygous for a knockout mutation die with severe hypoxia and extensive neuronal cell death, while gain of function mutations result in progressive seizure disorder. [provided by RefSeq, Nov 2016]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203