Nav1.8 Antibody: APC

Biorbyt

Nav1.8 antibody

16

1 microg/ml of SMC-342 was sufficient for detection of Nav1.8 in 10 microg of COS cell lysate transiently expressing Nav1.8 by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry

WB (1:1000), IHC (1:1000), ICC/IF (1:100) ICC, IF, IHC

Research Use Only

Monoclonal

S134

1 mg/ml

APC (Allophycocyanin)

Scn10a

sodium voltage-gated channel alpha subunit 10

Na(V)1.8; Nav1.8; peripheral nerve sodium channel 3; PN3; sensory neuron sodium channel; sodium channel protein type 10 subunit alpha; sodium channel protein type X subunit alpha; sodium channel type X alpha polypeptide; sodium channel voltage-gated type X alpha polypeptide; sodium channel, voltage-gated, type 10, alpha polypeptide; sodium channel, voltage-gated, type X, alpha subunit; voltage-gated sodium channel subunit alpha Nav1.8

Mouse

IgG2a

Sodium channel protein type 10 subunit alpha

Mouse monoclonal to Nav1 (APC). 8. Nav1. 8 is a voltage-gated sodium channel and plays a critical role in the generation and conduction of action potentials and is thus important for electrical signaling by most excitable cells. Therapeutically, the association of pain insensitivity with the loss of function of a certain sodium channel may have implications. Since Nav1. 8 is not present in cardiac muscle or neurons in the central nervous system, blockers of Nav1. 8 will not have direct action on these cells and thus can have less side effects than current pain medications. By performing more studies, there is a possibility to develop a new generation of drugs that can reduce the pain intensity in animals..

Human, Monkey, Mouse, Rat

See Manual

12352203