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Navitoclax-d8

HY-10087S
MedChem Express
CAS Number1217620-38-6
Product group Chemicals
Estimated Purity99.71
Molecular Weight982.66
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Navitoclax-d8 [1217620-38-6]
  • Delivery Days Customer
    10
  • CAS Number
    1217620-38-6
  • Estimated Purity
    99.71
  • Molecular Formula
    C47H47D8ClF3N5O6S3
  • Molecular Weight
    982.66
  • Scientific Description
    Navitoclax-d 8 is the deuterium labeled Navitoclax. Navitoclax (ABT-263) is a potent and orally active Bcl-2 family protein inhibitor that binds to multiple anti-apoptotic Bcl-2 family proteins, such as Bcl-xL, Bcl-2 and Bcl-w, with a Ki of less than 1 nM[1].
  • SMILES
    CC(C)(C1)CCC(C2=CC=C(C=C2)Cl)=C1CN3CCN(C4=CC=C(C=C4)C(NS(=O)(C5=CC(S(C(F)(F)F)(=O)=O)=C(C=C5)N[C@@H](CSC6=CC=CC=C6)CCN7C([2H])([2H])C([2H])([2H])OC([2H])([2H])C7([2H])[2H])=O)=O)CC3
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200