NB-360 [1262857-73-7]
T12188
CAS Number1262857-73-7
Product group Chemicals
Estimated Purity99.25%
Molecular Weight449.4
Overview
- SupplierTargetMol Chemicals
- Product NameNB-360 [1262857-73-7]
- Delivery Days Customer9
- CAS Number1262857-73-7
- Category SupplierChemical
- CertificationResearch Use Only
- Chemical NameNB-360
- Estimated Purity99.25%
- Molecular FormulaC21H19F4N5O2
- Molecular Weight449.4
- Scientific DescriptionNB-360 is a potent and brain-penetrable inhibitor of BACE1 and BACE2 with IC50s of 5, 5, and 6 nM for mouse and human BACE1 and BACE2. NB-360 exhibits excellent selectivity over the related aspartyl proteases pepsin, cathepsin E, and cathepsin D.
- Shelf life instruction3 years
- SMILESCc1cc(cnc1C(=O)Nc1ccc(F)c(c1)[C@]1(C)CO[C@](C)(C(N)=N1)C(F)(F)F)C#N
- Storage Instruction-20°C
- UNSPSC12352200