NBI-31772 (hydrate)

MedChem Express

NBI-31772 (hydrate)

10

Research Use Only

99.42

C17H11NO7.7/4H2O

372.82

NBI-31772 hydrate is a potent inhibitor of interaction between insulin-like growth factor (IGF) and IGF-binding proteins (IGFBPs) . NBI-31772 hydrate is also a nonpeptide ligand that releases bioactive IGF-I from the IGF-I/IGFBP-3 complex ( K i s=1-24 nM for all six human subtypes). Anxiolytic and antidepressant-like effects [1] [2] [3] .

O=C(C1=CC(O)=C(O)C=C1)C2=NC(C(O)=O)=CC3=C2C=C(O)C(O)=C3.O

2°C to 8°C

12352200