NBI-74330

MedChem Express

NBI-74330 [855527-92-3]

9

855527-92-3

Research Use Only

99.23

C32H27F4N5O3

605.58

NBI-74330 is a potent antagonist for CXCR3 , and exhibits potent inhibition of ( 125 I)CXCL10 and ( 125 I)CXCL11 specific binding with K i of 1.5 and 3.2 nM, respectively.

O=C(N([C@@H](C1=NC2=NC=CC=C2C(N1C3=CC=C(OCC)C=C3)=O)C)CC4=CC=CN=C4)CC5=CC=C(F)C(C(F)(F)F)=C5

-20°C,2°C to 8°C

12352200