NCAM / CD56 Antibody (clone MOC-1, Concentrated)

LifeSpan BioSciences

NCAM / CD56 Antibody (clone MOC-1, Concentrated)

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MOC-1 detects an isoform of the neural cell adhesion molecule (NCAM) expressed on natural killer (NK) cells of approximately 145 kD. NK cells make up approximately 10%-25% of peripheral blood lymphocytes, In addition, NCAM is expressed on a variety of neu

CD56 (MOC-1) can be applied in flow cytometry for analysis of blood samples and in immunohistochemistry using frozen sections and bone marrow aspirates. CD56 is applied in flow cytometry for the detection of NK cells in immune monitoring. In addition, the neoplastic counterpart of the NK cell can be characterized as T gamma lymphocytosis, showing expression of a number of antigens, e. g. CD56+, CD7+, CD16+, CD2+/- and CD8+/-. Co-expression of CD56 and CD138 )B-B4) is an indication of plasma cell malignancy in multiple myeloma, although it does not occur in all samples. In lung tumors, MOC-1 antibody is helpful in discriminating SCLC from non SCLC. The antibody is effectiveness formulated for direct immunofluorescent staining of human tissue for flow cytometric analysis using 10 ul/106 leukocytes. Since applications vary, each investigator should titrate the reagent to obtain optimal results.. Flo, IHC, IHC-Fr CD56 (MOC-1) can be applied in flow cytometry for analysis of blood samples and in immunohistochemistry using frozen sections and bone marrow aspirates. CD56 is applied in flow cytometry for the detection of NK cells in immune monitoring. In addition, the neoplastic counterpart of the NK cell can be characterized as T gamma lymphocytosis, showing expression of a number of antigens, e. g. CD56+, CD7+, CD16+, CD2+/- and CD8+/-. Co-expression of CD56 and CD138 )B-B4) is an indication of plasma cell malignancy in multiple myeloma, although it does not occur in all samples. In lung tumors, MOC-1 antibody is helpful in discriminating SCLC from non SCLC. The antibody is effectiveness formulated for direct immunofluorescent staining of human tissue for flow cytometric analysis using 10 ul/106 leukocytes. Since applications vary, each investigator should titrate the reagent to obtain optimal results.

Flow Cytometry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen

Research Use Only

Monoclonal

MOC-1

50 ug/ml

Unconjugated

...

NCAM1

neural cell adhesion molecule 1

antigen recognized by monoclonal antibody 5.1H11; CD56; MSK39; NCAM; neural cell adhesion molecule 1; neural cell adhesion molecule, NCAM

Mouse

IgG1

Human

2°C to 8°C

12352203