NCG21 [1079821-35-4]

TargetMol Chemicals

NCG21 [1079821-35-4]

16

Chemical

Research Use Only

NCG21

C23H24N2O3

376.45

NCG21 is a GPR120 agonist, which showed potent extracellular signal-regulated kinase (ERK) activation in a cloned GPR120 system. NCG21 potently activated ERK, intracellular calcium responses and GLP-1 secretion in murine enteroendocrine STC-1 cells that express GPR120 endogenously. Administration of NCG21 into the mouse colon caused an increase in plasma GLP-1 levels.

3 years

O=C(O)CCCC1=CC=C(OCCN(C2=NC=CC=C2)C=3C=CC=CC3)C=C1

-20°C

12352200